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Showing 1 to 12 of 285 entries
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A comparison of epitope repertoires associated with myasthenia gravis in humans and nonhuman hosts.

Autoimmune diseases

Vaughan K, Kim Y, Sette A.
PMID: 23243503
Autoimmune Dis. 2012;2012:403915. doi: 10.1155/2012/403915. Epub 2012 Dec 02.

Here we analyzed the molecular targets associated with myasthenia gravis (MG) immune responses, enabled by an immune epitope database (IEDB) inventory of approximately 600 MG-related epitopes derived from 175 references. The vast majority of epitopes were derived from the...

Evaluation of ENA-6 Profile by ELISA Immunoassay in Patients with Systemic Lupus Erythematodes.

Autoimmune diseases

Aganovic-Musinovic I, Karamehic J, Zecevic L, Gavrankapetanovic F, Avdagic N, Zaciragic A, Jukic T, Grcic N, Svrakic S.
PMID: 23097694
Autoimmune Dis. 2012;2012:321614. doi: 10.1155/2012/321614. Epub 2012 Oct 11.

Autoimmune diseases occur in 3-5% of the population. Study included 30 patients with clinically diagnosed SLE and 30 healthy controls (American college of Rheumatology, 1997). SLE was diagnosed according to criteria issued in 1997 by the American College of...

Magnetic Resonance Elastography for Liver Fibrosis in Methotrexate Treatment.

Open journal of rheumatology and autoimmune diseases

Hoganson DD, Chen J, Ehman RL, Talwalkar JA, Michet CJ, Yin M, Crowson CS, Matteson EL.
PMID: 26361561
Open J Rheumatol Autoimmune Dis. 2012 May;2(2):6-13. doi: 10.4236/ojra.2012.22003.

INTRODUCTION: Hepatic magnetic resonance elastography (MRE) allows for noninvasive assessment of liver fibrosis. The purpose of this study was to evaluate the usefulness of MRE in detecting and quantifying liver fibrosis in patients with rheumatoid arthritis (RA) who have...

Predisposition to Cervical Atypia in Systemic Lupus Erythematosus: A Clinical and Cytopathological Study.

Autoimmune diseases

Al-Sherbeni HH, Fahmy AM, Sherif N.
PMID: 26240757
Autoimmune Dis. 2015;2015:751853. doi: 10.1155/2015/751853. Epub 2015 Jul 09.

Introduction. Systemic lupus erythematosus (SLE) is a complex disease with variable presentations, course, and prognosis. The female genital tract may be a potential target organ in SLE since cervical inflammation may be associated with disease activity. An increase in...

Intravenous immunoglobulin treatment in chronic neurological diseases: do we have maintenance dose right?.

Autoimmune diseases

Dolezal O.
PMID: 25580286
Autoimmune Dis. 2014;2014:962530. doi: 10.1155/2014/962530. Epub 2014 Dec 18.

Objectives. We tried to define, on individual basis, minimal effective maintenance dose of intravenous immunoglobulins (IVIG) in 26 patients with chronic neurological conditions requiring long-term IVIG treatment. Methods. Clinical criteria were reviewed in individual cases (Phase 1) followed by...

Elements of the B cell signalosome are differentially affected by mercury intoxication.

Autoimmune diseases

Gill RF, McCabe MJ, Rosenspire AJ.
PMID: 24876949
Autoimmune Dis. 2014;2014:239358. doi: 10.1155/2014/239358. Epub 2014 May 04.

It has been suggested that environmental exposures to mercury contribute to autoimmune disease. Disruption of BCR signaling is associated with failure of central tolerance and autoimmunity, and we have previously shown that low levels of Hg(2+) interfere with BCR...

TNF-.

Open journal of rheumatology and autoimmune diseases

Simard JF, Mittleman MA, Shadick NA, Karlson EW.
PMID: 25019035
Open J Rheumatol Autoimmune Dis. 2012 May;2(2):14-20. doi: 10.4236/ojra.2012.22004.

BACKGROUND: Anti-TNF treatment may increase infection risk, although this has been difficult to study because the timing of anti-TNF treatment is driven by disease activity, which may influence infection susceptibility leading to confounding that varies over time. We evaluated...

Mechanism of Xinfeng Capsule on Adjuvant-Induced Arthritis via Analysis of Urinary Metabolomic Profiles.

Autoimmune diseases

Jiang H, Liu J, Wang T, Gao JR, Sun Y, Huang CB, Meng M, Qin XJ.
PMID: 26989506
Autoimmune Dis. 2016;2016:5690935. doi: 10.1155/2016/5690935. Epub 2016 Feb 18.

We aimed to explore the potential effects of Xinfeng capsule (XFC) on urine metabolic profiling in adjuvant-induced arthritis (AA) rats by using gas chromatography time-of-flight mass spectrometry (GC-TOF/MS). GC-TOF/MS technology was combined with multivariate statistical approaches, such as principal...

Risk Factors and Adverse Events Poorly Predict Infections and Hypogammaglobulinemia in Granulomatosis with Polyangiitis Patients Receiving Rituximab.

Autoimmune diseases

Besada E.
PMID: 26885383
Autoimmune Dis. 2016;2016:8095695. doi: 10.1155/2016/8095695. Epub 2016 Jan 18.

Background. 29 GPA patients from the Northern Norway vasculitis disease registry received rituximab (RTX) induction and maintenance. 24% and 31% had, respectively, severe and chronic infections while 45% had hypogammaglobulinemia and 28% discontinued RTX due to hypogammaglobulinemia. The aim...

Understanding and Managing Pregnancy in Patients with Lupus.

Autoimmune diseases

de Jesus GR, Mendoza-Pinto C, de Jesus NR, Dos Santos FC, Klumb EM, Carrasco MG, Levy RA.
PMID: 26246905
Autoimmune Dis. 2015;2015:943490. doi: 10.1155/2015/943490. Epub 2015 Jul 12.

Systemic lupus erythematosus (SLE) is a chronic, multisystemic autoimmune disease that occurs predominantly in women of fertile age. The association of SLE and pregnancy, mainly with active disease and especially with nephritis, has poorer pregnancy outcomes, with increased frequency...

Gender and Ethnicity Based Differences in Clinical and Laboratory Features of Myasthenia Gravis.

Autoimmune diseases

Abukhalil F, Mehta B, Saito E, Mehta S, McMurtray A.
PMID: 26175913
Autoimmune Dis. 2015;2015:197893. doi: 10.1155/2015/197893. Epub 2015 Jun 14.

Background. Previous reports describe ethnicity based differences in clinical and laboratory features between Caucasians and African Americans with myasthenia gravis. However, it is not known whether these findings apply to other ethnicities. Methods. Retrospective analysis of all patients treated...

Pathophysiological Relationship between Infections and Systemic Vasculitis.

Autoimmune diseases

Muñoz-Grajales C, Pineda JC.
PMID: 26236499
Autoimmune Dis. 2015;2015:286783. doi: 10.1155/2015/286783. Epub 2015 Jul 07.

The development of autoimmune disorders requires a combination of genetic, immunological, and environmental factors. Infectious agents, such as viruses and bacteria, can trigger autoimmunity through different mechanisms, and for systemic vasculitis in particular, microbial agents have been suggested to...

Showing 1 to 12 of 285 entries